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Abstract
Background: Staphylococcus aureus is one of the most important human pathogens that produces a wide range of toxins and causes various diseases. Staphylococcal enterotoxin is the most common cause of food poisoning. In addition, S. aureus enterotoxins are classified into 18 serotypes A to U based on serological and biological properties. Methods: The samples were isolated from clinical specimens and identified by routine bacteriological methods. The isolated S. aureus was evaluated by polymerase chain reaction (PCR) for the detection of the genes encoding SEA and SEA. Results: Based on the PCR results, 3 isolates possessed the enterotoxins B (SEB) gene while none of them showed enterotoxins A (SEA) gene. Conclusions: The obtained results revealed that the clinical samples might be a potential source of the enterotoxigenic strains of S. aureus.
Highlights
Staphylococcus aureus is one of the most important human pathogens that produces a wide range of toxins and causes various diseases
There is no precise mechanism that can explain the invasive diseases caused by S. aureus [3], S. aureus species produce a variety of exoproteins such as enterotoxins (SEs), toxic shock syndrome toxin 1 (TSST1), exfoliative toxins, hemolysin coagulase, and leukocidin
The showed enterotoxins A (SEA) and SEB genes in the isolates of S. aureus were determined by the polymerase chain reaction (PCR) method
Summary
Staphylococcus aureus is one of the most important human pathogens that produces a wide range of toxins and causes various diseases. Staphylococcus aureus is an important human pathogen, the virulence potential by which mainly relies on the production of an impressive set of protein toxins [1]. This pathogen can work separately or in concert to cause a multitude of human diseases. Sepsis-related infections, toxic shock syndrome, and food poisoning are among the diseases that have traditionally and been associated with the production of enterotoxins [2]. Enterotoxins are water-soluble proteins, which induce the non-specific
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