Abstract
The aim of this study was to investigate the potential of the forced oscillation technique (FOT) in the differential diagnosis of patients with obstructive and restrictive respiratory diseases. A total of 76 individuals was analysed, including moderate obstructive (MO; n = 18), severe obstructive (SO; n = 20), moderate restrictive (MR; n = 18) and severe restrictive (SR; n = 20) patients. The observed changes were consistent with previously published results and the physiological foundations involved. Analyses using receiver operator characteristic curves showed that resistance values provided adequate differentiation between patient groups with more advanced diseases (SO-MR and SO-SR), with diagnostic accuracy ≥0.80. The highest accuracy was offered by the respiratory system resonance frequency, which discriminated between the obstructive and restrictive groups accurately (≥0.84). Given the ease of performing the test, we can assume that the proposed methodology will provide a significant contribution to the differential diagnosis of obstructive and restrictive respiratory diseases.
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