Abstract

Background: In recent years the rate of cesarean section has significantly increased.To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section. Objectives: In our study, we aimed to evaluate the efficiency of prophylactic antibiotic administration by comparing three groups using single, multiple and no prophylactic antibiotic therapy. Materials and Methods: Our study is a prospective, randomized controlled study including emergent cases, that developed cesarean indication while in active labor, and elective cesarean cases. A total of 90 patients were included in the study, including 30 patients who underwent cesarean delivery and did not undergo an antibiotic prophylaxis (Group 1), 30 patients who underwent a single dose antibiotic prophylaxis (Group II) and 30 patients who underwent multiple dose antibiotic prophylaxis (Group III). Results: The incidence of wound infection was significantly higher in cases that were not using antibiotics at postoperative days 3, 5 and 7 compared to the cases using single and multiple antibiotics. There was not a significant difference between groups in terms of endometritis. Conclusion: Administration of prophylactic antibiotics prevent wound infection but does not prevent development of endometritis.

Highlights

  • In recent years the rate of cesarean section has significantly increased.To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section.antibiotics at postoperative days 3, 5 and 7 compared to the cases using single and multiple antibiotics

  • In our study, we aimed to evaluate the efficiency of prophylactic antibiotic administration by comparing three groups using single, multiple and no prophylactic antibiotic therapy

  • We aimed to evaluate the efficiency of prophylactic antibiotic administration by comparing groups that were administered single dose and multiple doses along with those who were not administered prophylactic antibiotic therapy

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Summary

Introduction

In recent years the rate of cesarean section has significantly increased.To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section.antibiotics at postoperative days 3, 5 and 7 compared to the cases using single and multiple antibiotics. In recent years the rate of cesarean section has significantly increased.To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section. Infection risk is significantly increased in women who undergo cesarean delivery compared to those who deliver vaginally. 20% due to demographic and obstetric factors.[1,2] the most significant risk factor for postpartum maternal infection is cesarean delivery.[3]. Hospitalization time increases due to the complications associated with infection following cesarean.[4]. Complications associated with infections following cesarean delivery are fever, wound infections, endometritis, bacteriemia, pelvic abscess, septic shock, necrotizing fascitis, septic pelvic vein thrombophlebitis and urinary system infections.[2,5,6] Endometritis and wound infections are still the most significant causes of postoperative infectious morbidity.[4] While the incidence of endometritis is between

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