Evaluation of the Efficacy of Polydioxanone Threads versus Autologous Plasma Gel for Infraorbital Rejuvenation

Abstract

Abstract Introduction Infraorbital dark circles refers to presence of darkness of the infraorbital region. Infraorbital dark circles possess no medical harm but signifies cosmetic and psychological burden. Various therapeutic modalities are prescribed for management of infraorbital dark circles without conclusive results. Aim of the Work compare between the efficacy and safety of PDO monothreads versus autologous plasma gel injections for infraorbital rejuvenation. Patients and Methods 40 patients with infraorbital dark circles were included. Patients under went plasma gel injections on the left eye, PDO threads treatment on right eye. All patients were assessed using 3D Antera camera before and after 1 month and 6 months of treatment. Results Both treatment modalities revealed marked cosmetic improvement. Both treatments showed marked response yet results on left eye were superior as regards wrinkle's size, indentation index, texture roughness and average melanin concentration. PDO thread insertion possessed marked significant improvement to wrinkle's size followed by indentation index then texture roughness and average melanin concentration. Plasma gel injection possessed marked significant improvement to wrinkle's depth followed by wrinkle's size then indentation index and finally texture roughness and average melanin concentration. Conclusion Both PDO thread insertion and plasma gel injection exerts beneficial effects in improving periorbital wrinkles and hyperpigmentation. However, plasma gel revealed more potent effects compared to PDO threads.