Abstract

Evaluation of The Efficacy of a Dietary Supplement in Alleviating Symptoms in Dogs with Osteoarthritis

Highlights

  • Osteoarthritis (OA), known as degenerative joint disease, is a condition common in both humans and companion animals that has been described for over a hundred years [1]

  • We investigated the anti-inflammatory and pain relief effects of a new canine diet supplement containing a mixture of Boswellia serrata Roxb., Curcuma longa, green tea extract, glucosamine, chondroitin sulfate, hyaluronic acid, and collagen type II-not hydrolised in dogs with osteoarthritis

  • Our findings suggest that our dietary supplement has beneficial effects in alleviating chronic orthopedic pain and in reducing clinical signs in dogs with osteoarthritis

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Summary

Introduction

Osteoarthritis (OA), known as degenerative joint disease, is a condition common in both humans and companion animals that has been described for over a hundred years [1]. The pathogenesis of canine OA involves changes in all tissues of the synovial joint. OA happens when trauma or cellular damage changes the normal homeostasis of the joint, releasing inflammatory mediators and degradative enzymes. Chronic pain and disability are the result of the deterioration of the articular cartilage. The most frequent causes of disease in dogs are the excessive exercise, trauma and/or genetic predisposition. In dogs aging more than 1 year, OA is very common. The course of OA is very slow; common findings are the degeneration of the cartilage, hypertrophy of bone at the margins and changes in the synovial membrane [2]

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