Abstract

Objectives: The study aimed at assessing the efficacy of neodymium laser therapies and Accutane (isotretinoin) systemic therapy for patients with rosacea. Materials and Methods: A total of 64 patients with rosacea were selected for the study for the treatment of facial rosacea; the study was conducted from 2016 to 2020. All patients underwent a thorough clinical examination according to the generally accepted scheme. Patients received neodymium laser therapies and Accutane (isotretinoin) systemic therapy. Investigator Global Assessment (IGA) scale, Laser Doppler Fluorometry (LDF), and Dermatology Life Quality Index (DLQI) questionnaire were used to assess outcome treatments, resulting in the rosacea of the scene before and after neodymium therapy and Accutane (isotretinoin) systemic therapy. Results: A multitargeted therapy effectiveness rosacea neodymium is ideal for the management of the signs and symptoms of rosacea and it results in reductions in the mean acne lesion counts after 7 seans therapy, with persistent reduction at the 12-month follow-up, indicating significant long-term remission. The average rosacea IGA scale decreased from 4.2 at baseline to 0.6 after treatment. The average indicators of DLQI before and after laser treatment were 17.3 and 2, 4 respectively. Laser Doppler imaging showed that the mean value of the facial area was 151 units, before treatment; after the treatment, the values decreased, and the mean was 129 units. Conclusion: Neodymium laser therapy exposure has been effective in treatment therapies for rosacea. Our results indicate that the use of neodymium monotherapy represents an option to consider when dealing with treatment rosacea, being effective, well tolerated, and free of side effects, as confirmed by clinical and instrumental evaluation. The condition improved from baseline in 92.3% of subjects.

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