Abstract
Chamomile (Matricaria recutita L) and Chrysanthemum (Chrysanthemum coronarium L. (Garland)) are plants belonging to the family Asteraceae. The pharmacological properties of these herbs result from interactions among their many components. Of these, over 120 secondary metabolites with pharmacological and/or potential pesticide activity have been identified. The diverse chemical and biological characteristics of this set of compounds, i.e., essential oils and organic extracts of genera Matricaria and Chrysanthemum, have been shown to have particular pesticidal effects, especially those rich in pyrethroids. This work characterizes chamomile and chrysanthemum extracts for their pesticidal properties and their effects following acute exposure in rats. Results show hepatotoxic and oxidative stress-inducing effects in the livers of rats exposed to C. coronarium extracts, but not those of M. recutita.
Highlights
Chamomile (Matricaria recutita L) and Chrysanthemum (Chrysanthemum coronarium L. (Garland)) are plants belonging to the family Asteraceae
The present work characterized extracts and found pyrethroid-type molecules likely responsible for the biocide activities of the products. This builds on previous studies that had identified such properties against mites (Tetranychus urticae K.) and insects (Musca domestica L.) at the Entomological Centre, INIA Chile
The study found that acute exposure of non-lethal doses of Matricaria recutita L extract presented minor hepatotoxic impact, given the lack of significant alteration to biomarkers
Summary
Chamomile (Matricaria recutita L) and Chrysanthemum (Chrysanthemum coronarium L. (Garland)) are plants belonging to the family Asteraceae. (Garland)) are plants belonging to the family Asteraceae. The pharmacological properties of these herbs result from interactions among their many components. Over 120 secondary metabolites with pharmacological and/or potential pesticide activity have been identified. The diverse chemical and biological characteristics of this set of compounds, i.e., essential oils and organic extracts of genera Matricaria and Chrysanthemum, have been shown to have particular pesticidal effects, especially those rich in pyrethroids. This work characterizes chamomile and chrysanthemum extracts for their pesticidal properties and their effects following acute exposure in rats. Results show hepatotoxic and oxidative stress-inducing effects in the livers of rats exposed to C. coronarium extracts, but not those of M. recutita
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