Evaluation of the Effect of Medications Used in Children with Rheumatic Diseases on Dental Maturation.

Ecem Ipek,Marmara University, Faculty Of Dentistry, Department Of Pedodontics, Istanbul, Turkey. ,Mehmet Oguz Borahan,Betul Sozeri,Başak Durmus,Marmara University, Faculty Of Dentistry, Department Of Oral And Maxillofacial Radiology, Istanbul, Turkey. ,Health Sciences University, Umraniye Training And Research Hospital, Department Of Pediatric Rheumatology, Istanbul, Turkey. ,Health Sciences University, Umraniye Training And Research Hospital, Department Of Pediatric Rheumatology, Istanbul, Turkey.

doi:10.55640/ijmsdh-10-04-33

Ecem Ipek, Marmara University, Faculty Of Dentistry, Department Of Pedodontics, Istanbul, Turkey. + Show 6 more

Open Access

https://doi.org/10.55640/ijmsdh-10-04-33

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Abstract

The study's main objective is to compare dental maturation in healthy children and those with rheumatic diseases. It also aims to determine the age of children with Pediatric Rheumatic Diseases (PRD), specifically focusing on comparing those receiving medical treatment to those who are not, and to differentiate between biological and non-biological medication recipients, to identify potential differences. This observational cross-sectional study was conducted to assess the dental maturation stages in a cohort of 278 children (126 boys, 152 girls) aged between 6 and 14 years between September 2021 and December 2023. The study population included individuals with PRD requiring dental treatment and systemically healthy children. Digital panoramic radiographs were utilized for the evaluation of dental maturation in both groups. A statistically perfect agreement was found among the dental age (DA) calculated by the researchers (ICC=1.000; p<0.01). A statistically perfect level of agreement was found between the chronological age (CA) of the cases and the DA measured by the Willems method (ICC=0.921; p<0.01). It was found that the difference between the estimated DA and CA was higher in girls and boys in the PRD group who were taking medication. No significant differences were found in DA estimated based on gender and treatment status among individuals with PRD. The Willems method tended to underestimate the age of girls receiving biological treatment while overestimating the age in all other groups.

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