Abstract
The aim of this study was to evaluate the effect of ethanol seed extract of Telfairia. occidentalis on the activity of liver enzymes in diabetic rats. Freshly harvested seed of T. occidentalis was processed into extract. Twenty (25) adult male wistar rats were divided into five (5) groups of five rats each. Group I was fed normal rat chow and water only, Group II was diabetic; untreated rats, Groups III and IV were diabetic; treated with 150 mg/kg and 250 mg/kg extract of T. occidentalis seed. The activity of serum hepatomarkers (Aspartate transaminase, Alanine amino transaminase and Alkaline phosphatase) evaluated was significantly (P<0.05) high which was reversed in a dose dependent manner. In conclusion, it has been unveiled through this study that T. occidentalis seed extract has the potential to improve hepatic health.
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