Evaluation of the detection performance of rotavirus-enteric adenovirus fluorescent nanoparticles combined test strip

Abstract

Objective To evaluate the sensitivity and specificity of rotavirus and enteric adenovirus antigen fluorescent nanoparticles rapid combined detection test strip. Methods The specimen including rotavirus, enteric adenovirus, and other enteric pathogens and 140 cases of patients with symptoms of gastrointestinal infection. The performance was analyzed after fluorescent nanoparticles rapid combined detection test strip and coloredmicrospheres rapid detection test strips were used to detect the same sample. Result The sensitivity of fluorescent nanoparticles rapid combined detection test strip is significantly higher than coloredmicrospheres rapid test strip and no specific reaction with Coxsachievirus (type A16), ECHO virus (type 30) and enterovirus (type 71). Conclusion The sensitivity of fluorescent nanoparticles rapid combined detection test strips is significantly higher than coloredmicrospheres rapid detection test strip, and the specificity is good. Key words: Adenoviridae; Rotavirus; Fluorescent nanoparticles; Coloredmicrospheres; Sensitivity and Specificity