Abstract
The main source of human exposure to organochlorines is through food, especially food with a high fat content, such as breast milk, which is critical for child hood development. Therefore, it is important to analyze milk and other biological matrices for organochlorine pesticides (OCPs), and then determine the source of the OCP contamination. The objective of this study was to evaluate the degree of contamination by OCP residues and their metabolites in breast milk samples from the municipalities of Mojuí dos Campos and Belterra-Pará, Brazil. The OCPs analyzed were dichlorodiphenyltrichloroethane (DDT) and its metabolites (o,p'-DDT, p,p'-DDT, o,p'-DDE, p,p'-DDE, o,p'-DDD, and p,p'-DDD), aldrin, endrin, dieldrin, hexachlorocyclohexanes (α-HCH, β-HCH, lindane (γ-HCH), and δ-HCH), endosulfan α and β, endosulfan sulfate, heptachlor, and heptachlor epoxide. These substances were analyzed in 22 breast milk samples using gas chromatography with an electron capture detector (GC-ECD). Seven were contaminated with p,p'-DDT and/or p,p'-DDE. The mean p,p'-DDT and p,p’-DDE content in the contaminated samples was 0.0022 and 0.0152 mg·kg-1 of milk, respectively. This contamination may have been due to the inadequate application of DDT until the end of the 1990s for the control of tropical diseases, including malaria. Despite being a preliminary study, the number of contaminated samples was significant, which suggests the need to expand this study to other environmental and biological matrices.
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