Abstract

ABSTRACT The cryosurgery is a very useful therapy for the treatment of a variety of neoplastic and non-neoplastic processes. Nevertheless, it is still poorly described as an option for the treatment of specific cutaneous neoplasms, such as squamous cell carcinoma. The purpose of the present study was to analyze the clinical response of cryosurgery for the treatment of squamous cell carcinoma in cats. For this 13 squamous cell carcinoma lesions were selected in 11 cats, diagnosed through citopathological and/or histopathological examinations. The lesions were frozen using liquid nitrogen spray, and the evaluations were performed in the moment of freeze and approximately every 15 days until the wound was completely healed. The response of cryosurgery was considered complete with tumoral remission on 38.5% of the cats, and partial on 46.1%. The main complications included crusting and nostril stenosis. The presented results suggested that cryosurgery is effective and may be a viable option for the treatment of squamous cell carcinoma in cats. The effectiveness of the therapy; however, depends on the correct selection of the candidates for cryosurgery based on the lesion size, and the attendance to some criteria, such as the freezing time and post-operative care.

Highlights

  • IntroductionThe procedure is considered safe, as it requires less anesthesia time (Queiroz and Matera, 2003)

  • Cryosurgery is a therapeutic modality for cutaneous neoplasms and consists of using controlled low temperatures to destroy neoplastic and non-neoplastic tissues (Eurides et al, 2008; Gage et al, 2009).The procedure is considered safe, as it requires less anesthesia time (Queiroz and Matera, 2003)

  • It presents better cosmetic results and lower morbidity than the conventional surgery (Hoffmann and Bischoff, 2001). This procedure is appropriate for the treatment of several superficial cutaneous lesions, such as benign and malignant neoplasms (Kufik, 1994; Zouboulis, 1998), and when conventional surgery cannot be performed due to associated comorbidities or anatomic location of the lesion (Ruslander et al, 1997)

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Summary

Introduction

The procedure is considered safe, as it requires less anesthesia time (Queiroz and Matera, 2003). It presents better cosmetic results and lower morbidity than the conventional surgery (Hoffmann and Bischoff, 2001). This procedure is appropriate for the treatment of several superficial cutaneous lesions, such as benign and malignant neoplasms (Kufik, 1994; Zouboulis, 1998), and when conventional surgery cannot be performed due to associated comorbidities or anatomic location of the lesion (Ruslander et al, 1997).

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