Evaluation of the correlation between glioma and a peritumoral edema zone

Abstract

Introduction and Aim: Peritumoral brain edema (PTBE), which is based on the interplay of vascular and parenchymal components, is the most frequent response that spontaneously arises in brain tumors. The goal of this study was to compare the dynamics of perifocal pathogenesis before and after surgery utilizing medication correction, as well as the relationship between glioma and the peritumoral edema zone. Methods: 500 patients with gliomas had clinical and morphological evaluations before and after surgery; each patient's operation was based on their unique histogenesis, levels of malignancy, size, and placement. Results: In this study, big meningiomas and other benign tumors do not exhibit PTBE, whereas gliomas do. However, there is no correlation between the size of the glioma and the severity of PTBE. Malignant brain tumors and benign tumors have a positive link with tumor histogenesis, but benign tumors have a negative correlation with PTBE severity. At the same time, we discovered a substantial inverse relationship between the density of gliomas and the severity of PTBE. Conclusion: The degree of gliomas and variations in the amount of free and bound water in the red cell mass and density are positively correlated with the severity of the peritumoral edema zone.