Abstract
Evaluation of the collagen-boosting effects of a Moldavian dragonhead extract.
Highlights
A flawless and young appearance of skin and hair is an important factor reflecting general well-being and, being a natural process, aging and obvious signs thereof are perceived as unhealthy
Our in-vitro study showed that treatment of mouse C2C12 cells with Moldavian dragonhead extract activates the innate longevity pathway involving the signaling kinase AMPK and the transcription factor fork head box protein O1 (FOXO1)
Moldavian dragonhead extract contains flavonoid glucuronides To assess the phytochemical constitution of the extract prepared from the aerial parts of Moldavian dragonhead, it was analyzed by chromatography followed by combined UV, mass spectrometry, and evaporative light scattering (ELS) detection
Summary
A flawless and young appearance of skin and hair is an important factor reflecting general well-being and, being a natural process, aging and obvious signs thereof are perceived as unhealthy. Multiple intrinsic and extrinsic factors affect skin health, leading to structural, metabolic, and physiological changes and visible signs of premature aging [41]. Implementing the rather novel concept of “beauty from within”, systemic treatment has been established for the prevention of visible skin aging in the past years, mostly involving hormone replacement or antioxidant therapy [8]. These treatments often harbor the risk of diverse side effects, which causes dissatisfaction in patients.
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