Abstract

Evaluation of the Association of Htr2a Gene Rs6313 Polymorphism with Heroin Dependence in a Sample from Northwest Iran

Highlights

  • relapsing disorder caused by a combination

  • Alterations in dopamine transport in the CNS are implicated in drug and alcohol dependence

  • the HTR2A rs6313 single nucleotide polymorphism plays an important role in drug dependence and abuse

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Summary

Introduction

Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. ‫همراهی چندشکلی ‪ rs6313‬ژن ‪ HTR2A‬و وابستگی به هروئین در نمونهای از جمعیت شمالغرب ایران است.‬ ‫مواد و روش ها: این مطالعه روی ‪ 100‬فرد بیمار وابسته به هروئین و ‪ 102‬فرد کنترل بدون وابستگی به مواد انجام شد.

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