Abstract
Ideally root canal irrigants should have, amongst other properties, antimicrobial action associated with a lack of toxicity against periapical tissues. Sodium hypochlorite (NaOCl) is a widely used root canal irrigant, however it has been shown to have a cytotoxic effect on vital tissue and therefore it is prudent to investigate alternative irrigants. Sterilox's Aquatine Alpha Electrolyte® belongs to the group of the super-oxidized waters; it consists of a mixture of oxidizing substances, and has been suggested to be used as root canal irrigant. Super-oxidized waters have been shown to provide efficient cleaning of root canal walls, and have been proposed to be used for the disinfection of medical equipment.ObjectiveTo compare the antimicrobial action against Enterococcus faecalis of NaOCl, Optident Sterilox Electrolyte Solution® and Sterilox's Aquatine Alpha Electrolyte® when used as irrigating solutions in a bovine root canal model.MethodologyRoot sections were prepared and inoculated with E. faecalis JH2-2. After 10 days of incubation the root canals were irrigated using one of three solutions (NaOCl, Optident Sterilox Electrolyte Solution® and Sterilox's Aquatine Alpha Electrolyte®) and subsequently sampled by grinding dentin using drills. The debris was placed in BHI broth and dilutions were plated onto fresh agar plates to quantify growth.ResultsSodium hypochlorite was the only irrigant to eliminate all bacteria. When the dilutions were made, although NaOCl was still statistically superior, Sterilox's Aquatine Alpha Electrolyte® solution was superior to Optident Sterilox Electrolyte Solution®.ConclusionUnder the conditions of this study Sterilox's Aquatine Alpha Electrolyte® appeared to have significantly more antimicrobial action compared to the Optident Sterilox Electrolyte Solution® alone, however NaOCl was the only solution able to consistently eradicate E. faecalis in the model.
Highlights
Endodontic irrigants should have, amongst other properties, a broad antimicrobial spectrum of activity against anaerobic and facultative microRUJDQLVPV JURZLQJ LQ ELR¿OPV DQG D UHODWLYH absence of toxicity against periapical tissues and oral mucosa[25]
The bacteria were morphologically identical to the E. faecalis used in the inoculum
This study evaluated the antimicrobial action of Sterilox’s Aquatine Alpha Electrolyte®, a commercially available super-oxidized water in the United Kingdom, in bovine root canals
Summary
Endodontic irrigants should have, amongst other properties, a broad antimicrobial spectrum of activity against anaerobic and facultative microRUJDQLVPV JURZLQJ LQ ELR¿OPV DQG D UHODWLYH absence of toxicity against periapical tissues and oral mucosa[25]. Sodium hypochlorite (NaOCl) is recommended as the main root canal irrigant because of its broad antimicrobial activity, the capacity to prevent formation of and dissolve the smear layer, in association with chelating agents, and its ability to dissolve tissue remnants[25].
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