Abstract
In this study, antifungal property of olive leaf extracts against Candida albicans PTCC-5027 was examined. Fresh olive leaf extracts were prepared using distilled water in a Soxhlet apparatus. The antifungal activity of the extract was analyzed by measuring the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC), using the microdilution test and disc diffusion assay. The olive leaf aqueous extracts exhibited antifungal effects against the yeast with an MIC of 24 mg/ml, MFC of 48 mg/ml, and inhibition zone diameter of 21 mm. The results indicated the sensitivity of Candida albicans PTCC-5027 to olive leaf aqueous extracts.
Highlights
Olive leaf extracts have been extensively used in medicine against microbial diseases [1]
The antifungal effect of olive leaf extracts growing in Iran was assessed against a standard C. albicans strain (PTCC-5027) through in vitro studies
The antifungal effect of olive leaf aqueous extracts on the tested yeast was quantitatively assessed by measuring minimum inhibitory concentration (MIC), minimum fungicidal concentration (MFC), and inhibition zone diameter
Summary
Olive leaf extracts have been extensively used in medicine against microbial diseases [1]. Olive leaf com-pounds such as oleuropein and its derivatives including hydroxytyrosol and tyrosol exhibit antimicrobial activities, which can reduce the risk of microbial infections. These compounds can inhibit viruses, retroviruses, bacteria, yeasts, fungi, molds, mycoplasmas, and other parasites, in the gastrointestinal and respiratory tracts [2,3,4]. The antifungal effect of olive leaf extracts growing in Iran was assessed against a standard C. albicans strain (PTCC-5027) through in vitro studies
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