Abstract
The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.
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