Abstract
DURING the past 30 years, many changes have occurred in the character and treatment of the disturbances of the thyroid gland. The changes in the treatment have been concerned mainly in the management of the patient with hyperthyroidism. However, it is a strange paradox that during the development of the antithyroid drugs the number of cases as well as the severity of the toxic goiter has gradually subsided. Now that we have the valuable antithyroid drugs, we rarely see the severely hyperthyroid patient. In fact, in our experience, the hyperthyroidism we have encountered has been so relatively mild that we have found a decreasing need for the thiourates. In our series of 1,473 cases, 861 patients, some of whom were adolescents, had variable degrees of hyperthyrodism in the form of true Graves's disease, exophthalmic goiter, and nodular goiter. Of the 861 patients, 21 were children under 16 years of age,
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