Evaluation of Some Biochemical Markers in Patients Serum of Myocardial Infarction and Heart Failure

Abstract

Heart disease is a common disease in the world and lead to the mortality. The aim of this study is to evaluate the diagnostic values of serum biochemical markers such as hs-CRP, LDH and myoglobin in patients with some heart diseases such as (AMI) and (HF). Hs-CRP and myoglobin were estimated by using a sandwich immune detection method, and LDH activity by enzymatic method using semi-automated chemistry analyzer. Our data revealed that serum hs-CRP, LDH, and myoglobin levels showed a high significant differences in patient groups compared with control group, whereas comparison patient groups between them also showed high significant differences except in hs-CRP levels they were indicates no significant values. Also LDH levels showed high significant in both patient groups compared with the levels of hs-CRP and myoglobin. Finally these parameters now play significant role in the diagnosis of disease and our finding suggest that the elevated levels of hs-CRP, LDH and myoglobin are a significant predictor and considered markers for myocardial damage and necrosis.