Evaluation of six widely Prescribed Antibiotics using ATC/DDD method in the Indonesian Hospital in Palestine: Retrospective study

Abstract

Purpose: The aim of this study to measure consumption of AB in ICU and medical department using defined daily dose which is an accepted standard method and provide data for rational use of antibiotics to decrease morbidity, mortality and resistance. Methods: The study was a retrospective in a state hospital with 120 beds. All patients treated with specific antibiotics on 1st December 2019 until 1st March 2020 were included in the study. Indications for antibiotic use and information about the patients were recorded on special forms. Antibiotic use were evaluated using the ATC/DDD index, which is also suggested by the WHO to be used in similar studies. Results: 234 patients were admitted to the medical and ICU department hospital, of whom 46 patient in the ICU. 96% OF the patients in ICU received AB and 92% of the patients in the medical department received AB. Those identified to use antibiotics with appropriate indications 40.7% in the medical department and 65.5% in the ICU department. The mean hospital stay was 3.4 days, of the total patients 42% of patient received AB less than three days. Conclusion: The rate of consumption of antibiotics is very high in our hospital and most of the prescribed drugs were irrational. Antibiotic stewardship should be constructed and activated in our country to control AB use, as this will decrease the emergence of resistant strains and decrease budget in hospitals and on the patients.