Evaluation of serum vitamin D levels in vitiligo patients

Abstract

Background: Recent studies have shown that vitamin D has an immune-protective effect. The role of vitamin D deficiency and VDR gene polymorphisms has been established in many autoimmune diseases, including vitiligo, but the results are still controversial. Aim of the study: To evaluate serum vitamin D levels in vitiligo patients. Materials and methods: For the study, we selected 60 clinically diagnosed cases of dermatology vitiligo and 60 controls which consisted of healthy volunteers with matched age and sex. A comprehensive history was obtained from each participant and each case was studied and closely reviewed. Results: The number of males in cases was 34 and the number of females in cases was 26. The number of males in controls was 33 and number of females was 27. The mean age of cases was 34.69 years and mean age of controls was 37.39 years. It was observed that vitamin D deficiency was seen in 51.6% cases and severe vitamin D deficiency was seen in 25% cases. On the contrary, normal vitamin D levels were seen in 66.7 % of controls and deficiency was seen in 26.6% of controls.