EVALUATION OF SERUM VITAMIN D LEVELS IN SEPSIS, CORRELATION WITH QSOFA SCORE AND CLINICAL OUTCOME.

Abstract

Aims - To study Vitamin D levels in sepsis, correlation of qSOFA score for assessing the severity of sepsis and predicting outcomes in patients of sepsis. Material And Methods - A cross sectional observational study was conducted at MLN Medical College, Prayagraj. A total of 140 patients were enrolled in the study after following inclusion and exclusion criteria's. Result – In the study, it was found that, higher values of qSOFA scores were found in the non-survivors patients (34.7% vs. 2.9%). Also higher value was associated with longer hospital stay and multiorgan dysfunction and ICU admission. In this study, it was also seen that higher values of serum Vitamin D was seen in survivors (27.9 ± 9.7 ng/dL v/s 9.7 ± 4.7 ng/dL; P < 0.0001).Also lower values were associated with longer hospital stay and multiorgan dysfunction and ICU admission. Conclusion – In this study, it was seen that higher values of qSOFA predicted poor clinical outcomes for patients with sepsis. Likewise, low S. Vitamin D levels were also associated with dismal clinical outcomes in sepsis.