Abstract
Objective: To evaluate serum levels of 25-hydroxyvitamin D (25-OHD) in patients with viral warts.
 Study Design: Comparative cross-sectional study.
 Place and Duration of Study: Dermatology Department, Fauji Foundation Hospital, Rawalpindi Pakistan, from Jul to Dec 2020.
 Methodology: One hundred patients were included in the study, 50 with viral warts (Group-1) and 50 without warts (Group2). Our study included both male and female patients of 10 to 60 years of age. Three categories were made according to their serum vitamin D levels. First, all participants were tested for serum vitamin D levels using ELISA.
 Results: In Group-1, 20(40%) had insufficient, and 25(50%) had deficient vitamin D levels. A statistically significant decrease in serum 25-OHD levels (p = 0.004) was found in patients with viral warts. In Group-2, 9(18%) had insufficient, and 2(4%) had deficient vitamin D levels. The mean serum vitamin D level was 22.61±10.11 in Group-1 and 45.12±24.60 in Group-2, resulting in a significant difference between patients with viral warts and those without viral warts regarding serum vitamin D levels (p=0.004).
 Conclusion: Patients with viral warts have deficient vitamin D levels.
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