EVALUATION OF SERUM IRON STATUS AND THYROID PROFILE IN PATIENTS OF CHRONIC KIDNEY DISEASE

Abstract

OBJECTIVE: To nd the prevalence and association of thyroid dysfunction with anemia/body iron status among Chronic kidney disease patients, MATERIALS AND METHODS:It is a cross-sectional study conducted in Government General Hospital ,Kurnool during the period from jan 2021-july 2021.. Atotal of 75 patients were included in our study who satised the diagnostic criteria of CKD and patients underwent clinical and renal parameters, haematological prole and iron status. For comparison of the results with the general population adequate number of controls were taken . RESULTS: Our study results showed that out of the 75 patients with CKD 49 patients had low T3 syndrome which accounts for 65% of the patients, 14 patients had low T4 syndrome) which accounts for 18% of the patients and 12 patients had primary hypothyroidism TSH >20µIU/ml. it was found that nearly 43% of the patients did not have target serum ferritin of 100 ng/ml and 49.2% of study population did not have target TSATof >20%. CONCLUSION: The study demonstrates a high prevalence of thyroid abnormalities particularly hypothyroidism, accompanied by increased prevalence of anemia and iron deciency indicating symbiotic relationship between thyroid gland function and body iron status. Thyroid Dysfunction occurred in the patients with chronic kidney disease, it does not indicate a state of hypothyroidism, but a reection of the state of chronic illness/malnutrition.