Abstract

This study aims to evaluate the serological, radiological and epidemiological analysis of suspected cystic echinococcosis patients, and to assess the positivity rate in the region. The retrospective study was conducted at Bursa Uludag University Hospital, Turkey and comprised data from January 2009 to December 2017 related to patients of either gender with suspected cystic echinococcosis who underwent indirect haemagglutination testing. Demographic and clinical data of patients who tested positive were analysed. Statistical analysis was done using SPSS 23. Of the 3910 patients with a mean age of 41.6±19.35 years (range: 0-93 years) who underwent indirect haemagglutination testing, 692(17.7%) tested positive; 390(56.4%) females, and 302(43.6%) males. The highest seropositivity rate 107(15.5%) was observed in 2011, followed by 104(15%) in 2016. Seropositive cases were predominantly seen in those aged 40-49 years 131 (18.9%), followed by those aged 50-59 years 124 (17.9%). Cystic echinococcosis was found to be a public health problem in South Marmara region of Turkey.

Highlights

  • MethodsThe retrospective, descriptive study was conducted at the Bursa Uludağ University

  • Bursa, Turkey, and comprised data from January 2009 to December 2017 related to patients of either gender with suspected cystic echinococcosis who underwent indirect haemagglutination testing

  • cystic echinococcosis (CE) affects humans and a variety of ungulates worldwide, and it is one of the 20 neglected tropical diseases listed by the World Health Organisation (WHO)[3,4]

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Summary

Methods

The retrospective, descriptive study was conducted at the Bursa Uludağ University. Hospital (BUUH) and comprised data from January 2009 to December 2017 related to patients haemagglutination (IHA) testing. The BUUH is an 880-bed tertiary referral hospital in. Bursa, which is the largest city in the South Marmara region in Turkey. After approval from the institutional ethics review committee, IHA results of suspected CE patients were obtained from various clinics. Demographic, clinical, laboratory, and follow-up data of the patients were taken from the hospital automation system. Age was categorised into 10-year brackets, starting from 0-9 years and moving up to 90-99 years. The antibodies in serum samples were detected using a commercial kit (Cellognost Echinococcosis test, Dade Behring, Marburg, Germany). The sera were diluted in V-bottom microplates and ≥1/64 titer level was evaluated as positive as per the manufacturer's recommendations[12]

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