Evaluation of serum fucose and protein bound fucose on myocardial infarction patients in Erbil city

Abstract

Background and objectives: L-fucose is a methyl pentose similar to L-galactose, except for the loss of the alcohol group on carbon No.6. It is found in human serum bound to proteins by covalent bonding and it is a member of a large group of compounds known as glycoproteins Glycoproteins determine and steer up the vital functions of plasma membranes, e.g. cell-cell recognition, growth control, information uptake mediated via hormones or toxins and the attachment of antibodies. The aim of the current study is to measure the serum concentrations of these parameters on both the healthy individuals and the myocardial infarction patients. Methods: The existing study has been initiated and implemented in earnest over the period commenced from February 2009 to October 2010 materialised on 100 healthy volunteer individuals countered to 110 (newly diagnosed myocardial infarction) patients. Serum total fucose and protein bound fucose were measured by UV/VIS spectrophotometery. Results: The mean concentrations of serum fucose and protein bound fucose were significantly being higher on my ocardial infarction patients versus those of the control individuals. Conclusion: in order to envisage the negative impact on the heart muscle can be judged by the increase in serum level of fucose and the subsequent protein bound fucose on the myocardial infarction patients, thus, they can be labelled as the biomarkered for the myocardial infarction.