Abstract
Results The average sE-selectin levels in the food allergy patient population were 54.0 +/- 21.6 ng/mL, while in the allergy-free population, the average sE-selectin levels were 57.7 +/-17.9 ng/mL. No statistically significant difference between sE-selectin levels was found between food allergy patients and patients with dyspeptic symptoms without concomitant food allergy (Mann-Whitney U-test, p =0.453028). In the food allergy patient population, average sPECAM-1 levels were 132.8 +/-31.4 ng/ ml, while in the allergy-free population average sPECAM-1 levels were 139.6 +/- 31.1 ng/ml. The analysis of the obtained results revealed no statistically significant difference between sPECAM-1 levels in food allergy patients and patients with dyspeptic symptoms without concomitant food allergy. Conclusions The results of examinations conducted in this study showed no statistically significant differences in serum PECAM-1 and E-selecine levels between the study groups.
Highlights
PECAM-1 (CD31) (Platelet Endothelial Cell Adhesion Molecule-1) is an adhesive molecule found on the side surfaces of endothelial cells and blood platelets, taking part in the cell adhesion processes
The goal of the study was to assess the sEselectin and sPECAM-1 levels in patients diagnosed with food allergies
Blood was collected from each subject for determination of the serum levels of the E-selectin and PECAM-1 adhesive molecules. sPECAM-1 and sE-selectin determinations were performed in a Bender MedSystems ELISA assay
Summary
The goal of the study was to assess the sEselectin and sPECAM-1 levels in patients diagnosed with food allergies
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