Evaluation of Salivary Alpha-Amylase level in Iraqi children with positive family history of hypertension

Suha Abd,Sumaiah Hussein,Maysaa Al-Malkey,Rasha Azeez

doi:10.33899/edusj.2021.168651

Abstract

This study accomplished to determine levels of salivary Alpha-Amylase (sAA) in Iraqi children with positive family history of hypertension, Hypertension was believed to be a risk factor in 18% of all deaths in 2010 (9.4 million globally). This study included one hundred children from primary school aged 6 to 13 years, with a focus in child welfare and family health history, with an emphasis on close relatives' hypertension reputations, with hypertension close relatives record categories identified by 1st and 2nd relatives, after documenting the full details, the burden was assessed for the children's families. The influence of age is confirmed by a correlation study of our own numbers, which shows a positive correlation. The disparity between age and salivary amylase level was important, with age group (12-13) years students having a higher mean salivary amylase level (309.7 U/L) than age group (6-7) years students (270.6 U/L). The gender outcome did not exceed statistical significance, but the gap was not important, which may be due to the limited sample size.

Highlights

One of the most important enzymes produced and secreted by salivary gland cells that respond to norepinephrine
The use of Salivary Alpha-Amylase (sAA) as a recent and effective instrument in the diagnosis of hypertension clinically and the determination of hyperactivity of sympathetic which thought to add to our understanding of the hyperadrenergic condition's functional role in hypertension
It has been proposed that Stress-related sympathetic activity in response to psychological and physiological stimuli is reflected by the salivary enzyme alpha-amylase [6, 1, 7 and 8]

Summary

Introduction

One of the most important enzymes produced and secreted by salivary gland cells that respond to norepinephrine. The use of sAA as a recent and effective instrument in the diagnosis of hypertension clinically and the determination of hyperactivity of sympathetic which thought to add to our understanding of the hyperadrenergic condition's functional role in hypertension. Non-pharmacological treatments are thought to be effective or pharmacological interventions in the treatment of hypertension will open up new possibilities as a non-invasive determinant for studying sympathetic dysfunction [3, 4, and 5]. It has been proposed that Stress-related sympathetic activity in response to psychological and physiological stimuli is reflected by the salivary enzyme alpha-amylase (sAA) [6, 1, 7 and 8]. There are two forms of elevated blood pressure: primary and secondary hypertension [12]. In 90-95 percent of cases, high blood pressure is caused by a person's diet and genetic factors [12,13]. Hypertension was thought to be the cause of 18% of all deaths (9.4 million worldwide) in 2010[17]

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