Abstract

SummaryMice infected with Candida albicans exhibited enhanced RES phagocytosis as measured by the clearance of colloidal carbon from the blood stream. Production of accelerated carbon clearance required living organisms. The time of onset of acceleration seemed to be dependent upon the size of the infecting inoculum and return to normal of the clearance occurred as the infection terminated. While accelerated clearance of colloidal carbon was produced by the infection, no change was seen at any time in the rate of clearance of microaggregated human serum albumin.We thank Mr. Joseph Edelin for his expert technical assistance.

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