Evaluation of restless legs syndrome and sleep disorders in patients with psoriatic arthritis.

Abstract

Restless legs syndrome (RLS) is aneurological disease with achronic course that is characterised by sleep disorders and sensorimotor impairment. The aim of this study was to evaluate the prevalence and severity of RLS in psoriatic arthritis (PSA) patients and those with psoriasis(P). The study included 50patients with psoriasis (28females, 22males), 50PSA patients (33females, 17males) and 50 healthy control subjects (34females, 16males), and all 3groups were matched with respect to age, gender and body mass index (BMI). Evaluations were made using the International RLS Rating Scale, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, Insomnia Severity Index, Fatigue Severity Scale (FSS), Beck Depression Index (BDI) and the SF-36 quality of life scores. RLS was determined at ahigher rate in the PSA patients (64.0%), compared to the Pgroup (20.0%, p < 0.001) and the control group (14.0%, p < 0.001). The number of moderate and severe RLS cases was significantly higher in the PSA group (68.7%) compared to the Pgroup (30%, p < 0.001) and the control group (0%, p < 0.001). In regression analysis, an independent correlation was found between the RLS score and PSQI (beta [β] = 0.269, p = 0.002), FSS (β = 0.243, p = 0.003), SF-36 physical score (β = 0.242, p = 0.004) and BDI (β = 0.177, p = 0.036). RLS was determined in PSA patients at ahigher rate than in psoriasis patients. The presence of RLS in PSA and psoriasis patients is related to impairments in sleep and quality of life, fatigue and depression.