Evaluation of Renal Function Status in Type II Diabetic Patients at Khartoum State, Sudan

Abstract

Background: ‏ Type II Diabetes mellitus is the most common type of DM which constitute about 85-95% of all Diabetes mellitus cases. Diabetic nephropathy is the kidney disease that occurs as a result of diabetes complication. The aim of this study was to evaluate the renal function status in Sudanese type 2 diabetic patients at Khartoum state, Sudan.
 Materials and Method: This study was analytical case control hospital-based study conducted at International University of Africa Hospital, Khartoum state, Sudan, during the period from February to May 2022. Type II diabetic patients who attended at International University of Africa Hospital during aforementioned period were included. In addition to that, healthy participants were selected as control group. A total of 2.5 ml of whole blood was collected from each participant and dispensed into heparin anticoagulated containers for Blood urea and serum creatinine measurement. Measurement of blood urea and serum creatinine was done by using Biochemistry analyzer (Myndray-BS200).
 Results: When compared some renal function parameters between cases and control group, the results revealed that the mean blood urea, serum creatinine levels and blood glucose (random) concentration of the case group were significantly high when compared with the control group (0.000). In Gender-wise correlation of renal function tests (RFT) in the cases, the results showed that male patients had higher blood urea and serum creatinine levels when compared with female patients.
 Conclusion: Our results of the renal function tests examined; showed significant increase in blood urea, serum creatinine and blood sugar when compared with non-diabetic patients, which indicates abnormality in renal function status.
 Keywords: Blood urea, creatinine, diabetes, type II diabetes, DM, renal failure, kidney, hyperglycemia, renal function tests, glucose, random blood glucose