Evaluation of Relationship between Nonalcoholic Fatty Liver and Coronary Artery Disease Severity by Multidetector Computed Tomography

Abstract

AbstractBackground: Coronary Heart Disease (CHD) is considered to be a leading cause of morbidity and mortality worldwide, so early detection of CHD in asymptomatic individuals is required. Several metabolic risk factors contribute to devel-opment of both Nonalcoholic Fatty Liver Disease (NAFLD) and CHD.Aim of Study: To evaluate the association between (NAFLD) and (CAD) severity.Material and Methods: This study included thirty patients with symptoms suggestive of ischemic heart disease. All patients were subjected to clinical evaluation, coronary CT angiography and Gensini score was used to assess the coronary artery disease severity. Ultrasound examination of the liver to assess the hepatic steatosis.Results: Among thirty patients enrolled in our study 13 patients had positive coronary findings 9 of them showed also hepatic steatosis. The association between NAFLD and CAD was significant as regard the age (p=0.010), BMI (p=0.011). And diabetes mellitus (p=0.011). In comparison with the normal group. There was significant association between Gensini score and grading of fatty liver infiltration (p-value=0.017).Conclusion: There was high prevalence of NAFLD in patients with documented CAD (69.2%) with significant association between Gensini score and grading of fatty liver infiltration.