Abstract

In 1963, Easson and Russell<sup>27</sup>reported that 13% of 822 patients with Hodgkin's disease were alive at 15 years and were presumably cured by radiotherapy. Curative therapy became the primary clinical objective in Hodgkin's disease, replacing symptomatic amelioration. Improved clinical staging and histological classification facilitated therapeutic management. In a report by Peters et al,<sup>28</sup>of 1,131 patients treated with radiotherapy from 1931 to 1969, the five-year survival rate was 43%. During the period from 1965 to 1969, with the completion of five years of observation of 64 patients, the survival was 59%; it is stated that 40% of these patients were in stages I and II of the disease. The radiotherapy center at Stanford<sup>29</sup>reports 275 patients with Hodgkin's disease, of whom 54 have completed five years of observation. The five-year survival was 73%; however, 80% of the patients were in stages I and II of the

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