Abstract

BackgroundThis study investigated the agreement between a new rebound tonometer, IC200, and IcarePRO and Goldmann applanation tonometry (GAT).MethodsThis was a prospective cross-sectional study. We measured the intraocular pressure (IOP) in 145 eyes of 145 glaucoma patients in the sitting position using GAT, IcarePRO, and IC200. IcarePRO and IC200 measurements were also obtained in the supine position. IC200 measurement was performed using two modes: single six (IC200-single) and automatic (IC200-continuous) six-measurements mode.ResultsAll tonometers provided high reproducibility in both positions (all intraclass correlation coefficients > 0.90), although it was highest with GAT, followed by IC200-continuous and IC200-single and then IcarePRO. In the sitting position, the mean (± SD) IOPs of GAT, IcarePRO, IC200-single, and IC200-continuous were 14.5 ± 2.9 mmHg, 13.3 ± 3.2 mmHg, 11.6 ± 3.2 mmHg, and 11.5 ± 3.2 mmHg, respectively. IOPs measured with IcarePRO or IC200 were significantly lower than those with GAT, particularly in patients with low IOP. IOPs measured with all tonometers were significantly elevated in the supine position as compared with the sitting position, but this difference was significantly greater with IC200-single and IC200-continuous compared with IcarePRO. IOP elevation was significant in eyes without bleb versus those with bleb, but this finding was not observed when IOP was measured with IcarePRO. The IOPs of the single and continuous modes of IC200 were interchangeable in both positions.ConclusionsGAT, IcarePRO, and IC200 had sufficiently high reproducibility, but measurements with IcarePRO may not be accurate in the supine position. Elevation of IOP in the supine position, especially in eyes with bleb, was more sensitively captured with IC200 than with IcarePRO.Trial registrationJapan Clinical Trials Register, No. UMIN000039982.

Highlights

  • This study investigated the agreement between a new rebound tonometer, IC200, and IcarePRO and Goldmann applanation tonometry (GAT)

  • Because a 1-mmHg increase in intraocular pressure (IOP) increases the risk of the development glaucoma by 10 to 18% [3,4,5] and a 1-mmHg decrease in IOP reduces the progression of glaucoma by 10% [6], an accurate measurement of IOP is undoubtedly essential for glaucoma patients

  • The accurate measurement of IOP is especially important in pediatric glaucoma because it is typically performed on a bed with the patient under general anesthesia

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Summary

Introduction

This study investigated the agreement between a new rebound tonometer, IC200, and IcarePRO and Goldmann applanation tonometry (GAT). The Goldmann applanation tonometer (GAT) has been the gold standard for the measurement of IOP, a series of rebound tonometers can measure IOP more objectively than other tonometers and without the use of topical anesthesia. These devices enable the measurement of IOP even in bedridden patients, which is important in patient populations with a growing life expectancy. The Icare tonometer series includes IcareTA01i, IcarePRO, IcareHOME, and IC100, but a direct measurement of IOP in the supine position is available only with IcarePRO Among these rebound tonometers, the IOP measured with IcarePRO has the closest agreement with the IOP measured with GAT [7]. The second aim of the study was to investigate the effect of various ocular biomechanical parameters, such as central corneal thickness, on these measurements

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