Abstract
The purpose of this paper is to present the data obtained from the study of 152 persons suspected clinically of having some alteration in thyroid function. Within a few days the basal metabolic rate and proteinbound blood iodine level were determined and a study of the radioactive iodine uptake by the thyroid made in each case. These results were then analyzed in relation to the immediate clinical picture and the subsequent clinical course of each patient. In the diagnosis of thyroid dysfunction, measurement of the basal metabolic rate has long been utilized as an office screening procedure. Its accuracy is limited, according to Roth and Roth, 1 by certain standard conditions required of the physician, the apparatus and, more important, the patient. Moreover, many types of patients have been found to be unsuited for this test (that is, asthmatic, neurotic and psychotic patients, children and patients with cardiac decompensation). A
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