Year-end Sale % OFF 
Abstract
BackgroundTo explore the value of parameters of multiphase dynamic contrast-enhanced magnetic resonance imaging (MDCE-MRI) in the qualitative diagnosis of hepatic masses.MethodsEighty patients with hepatic masses were retrospectively analyzed. All the patients underwent MDCE-MRI at 3.0 T MR before treatment. Mean enhancement time (MET), positive enhancement integral (PEI), a maximum slope of increase (MSI), and a maximum slope of decrease (MSD) were measured.ResultsThere were significant differences between benign and malignant hepatic masses with respect to MET, PEI, and MSI values. The PEI and MSI values between hemangiomas, hepatocellular carcinomas (HCCs), cholangiocarcinomas, and metastatic tumors had significant differences. The MSD value between metastatic tumors, HCCs, and hemangiomas were significantly different. The area under the curve (AUC) values of the receiver operator characteristic curves for MET, PEI, and MSI were 0.70, 0.72, and 0.80, respectively. The specificity of MET, PEI, and MSI were all 77%, and the sensitivities of MSI was the highest, of which was 82.40%. Logistic regression analysis showed the regression equation to be P = 1/[1 + e0.008 × 1 + 0.007 × 2–6.707], and taking the Youden index maximum points as a diagnostic point was 0.2946.ConclusionSome parameters of MDCE-MRI have significant roles in differentiating hepatic masses.
Highlights
To explore the value of parameters of multiphase dynamic contrast-enhanced magnetic resonance imaging (MDCE-MRI) in the qualitative diagnosis of hepatic masses
It is important to make a correct diagnosis, especially when the potential for therapy exists. While most of these lesions present as solitary masses, multiple lesions may be seen in patients with hemangiomas, hepatocellular carcinomas (HCCs), cholangiocarcinomas, and metastatic tumors
Comparison of benign and malignant hepatic tumors The Mean enhancement time (MET), positive enhancement integral (PEI), and maximum slope of increase (MSI) values were significantly lower in the malignant hepatic tumor group than that in the benign tumor group (Table 1)
Summary
To explore the value of parameters of multiphase dynamic contrast-enhanced magnetic resonance imaging (MDCE-MRI) in the qualitative diagnosis of hepatic masses. There are numerous causes of solid hepatic masses, both benign and malignant. It is important to make a correct diagnosis, especially when the potential for therapy exists. While most of these lesions present as solitary masses, multiple lesions may be seen in patients with hemangiomas, hepatocellular carcinomas (HCCs), cholangiocarcinomas, and metastatic tumors. The positive predictive value of alpha-fetoprotein (AFP) in the diagnosis of primary liver cancer is only 67.8–74.4% [2]. Biopsy and histopathologic verification are mandatory for the definitive diagnosis of hepatic masses, those cannot be regarded as ideal diagnostic methods as invasive procedures
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
