Abstract
This study assessed QOL, cognitive profile, and psychiatric symptoms before and after open heart surgery. The prospective study was conducted at the Faisalabad Institute of Cardiology from January 2022 to January 2023. A total of 95 patients were included in the study. All patients underwent neurological and physical evaluations. Every measure was assessed preoperatively and postoperatively. The effects of treatment-related factors and patient-related ones were analyzed. 27 (28%) patients had preoperative anxiety, which decreased to 10 (10.5%) after 1 week of surgery and to 6 (6.3%) after 6 months. 18 (18.9%) patients had preoperative depressive symptoms, which decreased to 7 (7.3%) patients after 1 week of surgery and 6 (6.3%) after 6 months. There was a significant improvement in the mean value of anxiety over the study period (P<.001). Regarding depressive symptoms, there was no significant improvement after 1 week (P<.208). Diabetes mellitus and age were inverselycorrelated with anxiety and depression; this correlation was statistically significant. Delirium, ischemic time, total bypass time, age, and hypertension were significant predictive factors of cognitive performance. Based on the results, it can be concluded that anxiety and depression adversely impacted the quality of life and were improved gradually over time. Cognitive function declined early after surgery and improved after 6 months.
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