Evaluation of Prostate Volume and Shape Change after Permanent Prostate Brachytherapy Using a Novel Deformable Registration Method

Abstract

Prostate volume and shape change both during and after permanent prostate brachytherapy (PPB), mainly due to edema. Many studies have investigated how prostate volume changes from day 1 to day 30 or later. There is no available information on how prostate volume changes from immediately post-implantation to post-implant imaging. When determining implantation quality at end of procedure using intraoperative dynamic dosimetry techniques, the knowledge of potential prostate volume and shape changes from end of implantation to time of post-implant imaging would be valuable.