Evaluation of Prescription Pattern and Medication Adherence in Patients with Alcoholic Liver Disease

Abstract

Background: ALD is the most common cause of morbidity and mortality among patients. A patient’s Medication Non-Adherence may also interfere with the progression of Disease. Analysis of Prescription pattern in ALD helps to ensure the safety of the Patient by assessing the signs and symptoms of disease and its appropriate therapy. Thus, educating the patients regarding their clinical condition will have a significant role in reducing the severity of the disease. Aim: To assess the Prescription pattern, Medication Adherence and to identify the correlation between the medication adherence and the educational status in ALD patients. Materials and Methods: The Study was a Prospective Observational study carried out for a duration of Six months. Morisky Green Levine scale was the tool used to assess the medication adherence. Data was collected using a self-designed data collection form. Results: A Total of 160 Alcoholic subjects were assessed during the study period among which 65.62% of them were illiterate. Out of total cases 76.87 % of hepatoprotective drugs, 50.62% antiemetics, 38% vitamins and 11% of anti-ulcer drugs were prescribed among patients. It was found that there exist a relationship between educational status and medication adherence (P-value: 0.0021). Conclusion: The study helped to assess the different class of drugs, drugs used in different comorbid conditions and also to evaluate, identify and solve the problems associated with the Medication Non-Adherence of the patients.
 Keywords: Medication Adherence, Alcoholic Liver Disease, Rational Drug Therapy.