Abstract

With continuing developments in the field of neonatology, survival rates of low birth weight and small for gestational age infants have increased, which in turn has brought important prematurity-related problems. The aim of this study was to evaluate retrospectively the prematurity problems that are the significant causes of morbidity and mortality. 613 premature infants hospitalized in the neonatal intensive care unit of Ataturk University Medical Faculty Hospital between January 2010 and January 2012 were included in this study. Infants were divided into groups according to their birth weight and gestational age. 323 infants were male (52.6%) and 290 were female (47.4%). 63.9% of infants weighed ≥1500 grams, and 58.5% had a gestational age of ≥33 weeks. Respiratory distress syndrome (RDS) was detected in 249 (40.6%), bronchopulmonary dysplasia (BPD) in 124 (20.2%), necrotizing enterocolitis (NEC) in 41 (6.6%), retinopathy of prematurity (ROP) in 202 (32.9%), and intracranial hemorrhage (ICH) in 15 (2.4%). RDS, BPD, NEC, ROP, and ICH rates were inversely proportional to decreases in gestational age and birth weight, and were found to be statistically significant. Mortality and morbidity rates were similar to the other data published from our country, but the rates were above those reported in developed countries. We believe that our morbidity and mortality rates can reach levels comparable to those of developed countries with improved antenatal care, regular follow-up of pregnancy and increased numbers of physicians and health care personnel per patient.

Highlights

  • Preterm delivery is among the leading causes of neonatal mortality and morbidity globally, including in developed countries

  • respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), retinopathy of prematurity (ROP), and intracranial hemorrhage (ICH) rates were inversely proportional to decreases in gestational age and birth weight, and were found to be statistically significant

  • Mortality and morbidity rates were similar to the other data published from our country, but the rates were above those reported in developed countries

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Summary

Introduction

Preterm delivery is among the leading causes of neonatal mortality and morbidity globally, including in developed countries. Thanks to the scientific and technological advances in the field of neonatology, leading to an increased quality of neonatal intensive care unit care, perinatal mortality among premature babies has been reduced, in developed countries [1]. Based on the recent statistics issued in the United States, the premature delivery rate was reported to be 12% in 2007 [2]. Despite all the advances in neonatal and perinatal care, the morbidity among preterm babies remains a significant issue. Immune and genitourinary system disorders, respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), intracranial hemorrhage (ICH), patent ductus arteriosus (PDA), retinopathy of prematurity (ROP), and necrotizing enterocolitis (NEC) [4]

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