Abstract
Background: Dental bleaching has become one of the most demanded aesthetic procedures as it is very simple and gives fast results that satisfy the patient’s wishes. However, unfortunately, it has the annoying side effect of tooth sensitivity. This clinical trial was designed to evaluate the efficacy of using a desensitizing agent, which was applied during in-office bleaching with 30% HP (hydrogen peroxide). Methods: 36 participants were divided into four groups (N = 9). According to the intended intervention as follows: Group I:—Application of Relief ®Amorphous Calcium Phosphate (ACP) before in-office bleaching; Group II—Application of Relief ®ACP before and after in-office bleaching; Group III—Application of Relief ®ACP after in-office bleaching; and Group IV: placebo was applied before and after in-office bleaching. Then, three hydrogen peroxide bleaching applications for a total of 45 minutes were performed. The primary outcome variable was hypersensitivity, assessed with (VAS) scale immediately and 24h, 1 week and 1 month after the procedure; while the secondary outcome was teeth shade assessed using the VITAPAN ® classical shade guide. Results: Statistical analysis was done using Kolmogorov-Smirnov, Shapiro-Wilk tests, Kruskal-Wallis test and Dunn’s test. Immediately after bleaching, there was statistically significant distinction in the median pain score between the groups. After 1 day, the ACP gel before and after bleaching group showed the lowest median score, while, the control group confirmed the highest median score. After 2 days, no statistically sizable difference was observed between all groups. The group receiving ACP gel before and after showed the highest change in median of classical shade guide scores while, (ACP gel after) and control group; showed the lowest change. Conclusion: The application of the desensitizing agent prior to and after in–office bleaching was successful in lowering post-bleaching hypersensitivity. Trail Registration: Clinical trial.gov NCT02942082 21/10/2016
Highlights
In-office bleaching permits close professional control, prevents material ingestion, reduces the total treatment time, and has the potential for quick results, improving patient satisfaction1
The objective of this randomized clinical trial is to assess whether the use of a desensitizing agent will diminish the tooth sensitivity induced by dental bleaching
Patient ages ranged between 18–40 years old; their mean ages were 32.4± 4.3, 32.1 ± 4.4, 33.1 ± 4.8 and 32.1± 5.3 for the amorphous calcium phosphate (ACP) gel before bleaching group, ACP gel before and after bleaching group, ACP gel after bleaching and the control group, respectively, with no statistically significant difference regarding mean age values (P-value = 0.965) between all groups
Summary
In-office bleaching permits close professional control, prevents material ingestion, reduces the total treatment time, and has the potential for quick results, improving patient satisfaction1 Be that as it may, tooth sensitivity (TS) is the most common side-effect of dental bleaching. Bioactive materials such as ACP (amorphous calcium phosphate) and CCP-ACP (casein phosphopeptite and amorphous calcium phosphate) as desensitizers and re-mineralizing specialists have been utilized for this purpose; there is only limited research in this area7 The objective of this randomized clinical trial is to assess whether the use of a desensitizing agent will diminish the tooth sensitivity induced by dental bleaching. Dental bleaching has become one of the most demanded aesthetic procedures as it is very simple and gives fast results that satisfy the patient’s wishes It has the annoying side effect of tooth sensitivity. The group receiving ACP gel before and after showed the Invited Reviewers version 1
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