Evaluation of polysomnographic diagnostic criteria for obstructive sleep apnea syndrome in children

Abstract

Objective: To determine the appropriate criteria of obstructive sleep apnea syndrome (OSAS) in children. Method: Children with snoring and healthy children were recruited from October 2014 to September 2015. Subjects were divided into four groups based on polysomnography(PSG). Group 1: children with obstructive apnea hypopnea index(OAHI)≥1 (the OSAS criteria of the International Classification of Sleep Disorders, ICSD) but their AHI≤5 or OAI ≤1 (under the OSAS criteria of AHI>5 or OAI>1 by the American Thoracic Society, ATS); Group 2: children with OAHI<1 (the primary snoring criteria of the ICSD); Group 3: children with AHI>5 or OAI>1; and Group 4: normal children as controls. Sleep disorder scales and polysomnography parameters were compared among the four groups. Results: A total of 1 115 children were included.There were 143, 345, 529 and 98 children in each group. After adjust for age, gender and body mass index(BMI), children in group 1 had higher total sleep disorder scale score (P<0.01), as well as sub-scores for severe snoring (P<0.01), daytime behavior problem (P<0.01) and sleep related nighttime abnormality (P<0.05) compared with normal controls, and they had longer mean and longest duration of obstructive apnea and hypopnea and lower minimum oxygen saturation compared with children with obstructive AHI<1 (all P<0.05 or <0.01). Conclusion: OAHI>1 should be defined as the criteria of OSAS in children.