Abstract
To evaluate abdominal ventral wound healing by using a specific biomaterial, a handmade polyamide surgical mesh. A surgical incisional defect was made in ten rabbits to simulate a hernia in the ventral abdominal musculature. A polyamide surgical mesh was used in hernioplasty. They were monitored for surgical wound healing, and macroscopically and histologically evaluated at the end of the experiment. The polyamide surgical mesh did not cause foreign body reaction, pain, edema, or infection in the surgical site. The manure production was not affected by intestinal tissue adherences to the mesh, consistent with the ultrasonography result where adherences were not observed and organized scarring tissue formed in the incisional defect. The polyamide mesh was fixed over the abdominal wall, and its external and internal sides were surrounded by a vascularized connective tissue. None of the experimental animals developed adherences from internal organs to the polyamide mesh, except two rabbits where the omentum formed adherence to the internal scarring tissue without present herniation or compromise of the rabbit's health. Polyamide surgical mesh for hernioplasty presents, in rabbits, excellent biocompatibility, with minimal body adverse reactions and low cost.
Highlights
Hernias are organ protrusions surrounded by peritoneum through a natural hole
Incisional hernia consists of the viscera protrusion through areas of the abdominal wall abnormally weakened by trauma and surgical incisions[2]
The polyamide mesh over the created defect in the abdominal ventral musculature preserved the anatomy of the abdominal wall and barred the intra-abdominal organs to go through the created defect
Summary
Hernias are organ protrusions surrounded by peritoneum through a natural hole They have high incidences in people and domestic animals, and named in accordance with their localization. The benefits of polypropylene in comparison with biomaterials from animal tissues such as equine pericardium or equine central diaphragm tendon preserved in 98% glycerin are its resistance, absence of bioreactivity and degradation, and elasticity, which allows better equilibrium in the tension distribution. It is a high-cost option and can cause postsurgical complications such as infections, septicemia, intra-abdominal organ injury, and adherences[7]. Positioning the polypropylene mesh in direct contact with the intraperitoneal viscera can form adhesions and fistulas, which occur in 80–90% of human patients[6,8]
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