Abstract

Background The Patient Reported Outcomes Measurement Information System (PROMIS) is a tool developed by the National Institutes of Health that allows comparisons across conditions or even the United States (U.S.) general population. Objectives Our purpose was to compare PROMIS outcomes between patients who underwent a planned resection to those who underwent an initial unplanned excision of their sarcoma followed by a definitive oncologic resection. We then compared these groups to the U.S. general population. Methods Eighty-five patients were included and were divided into those who underwent an initial planned resection (67) and unplanned excision (18). These patients were then further categorized based on the length of follow-up since their last surgery, either early (<12 months) or late (>12 months). Results We evaluated seven PROMIS domains and found no differences between patients who underwent planned resection versus those who underwent an initial unplanned excision followed by a wide resection of the previous wound bed. When compared to the U.S. population, both cohorts demonstrated significantly improved scores in several emotional health domains. Conclusions Patients who undergo an unplanned excision followed by a definitive oncologic procedure have similar PROMIS scores compared to patients who undergo an initial planned resection.

Highlights

  • Introduction e Patient Reported Outcomes MeasurementInformation System (PROMIS) is an outcome tool that was developed by the United States (U.S.) National Institutes of Health

  • There was no significant difference in postoperative complications between cohorts or average resection size (Table 1). e average resection size was based on the pathologic sample obtained during the definitive oncologic procedure. is included the tumor for the planned surgical resection and the wound bed for the unplanned excision cohorts

  • We attempted to answer whether there was a difference in Patient Reported Outcomes Measurement Information System (PROMIS) scores between these patient cohorts, as well as if these scores differed from the United States general population

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Summary

Introduction

Information System (PROMIS) is an outcome tool that was developed by the United States (U.S.) National Institutes of Health. It is a patient-reported tool that categorizes responses into health domains. In converting individual patient responses to T-scores, a researcher can evaluate the health impact a rare entity such as a sarcoma has on a patient’s life and compare this to a more common disease process, or even the U.S general population [1]. In evaluating outcomes with the PROMIS tool, a lower score signifies less of the tested function; for example, if a patient scored 40 in the physical function domain, they would have a lower physical function level compared to the U.S general population. A score of 40 in the depression domain would indicate that the patient has a lower level of depression. e desired score is dependent on the domain being tested [2]

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