Abstract

Plants are one of the most abundant sources of potentially useful chemical compounds and medicinal properties. As a result, over the last few decades, the market for plant research has been steadily increasing all over the world. The future pharmacological behaviours of Cyperus rotundus Linn. are assessed using a literature review as a basis. Extracts from various sections of the plant (aerial component, tuber, rhizomes, etc.) produce significant amounts of medicinal active compounds, as well as the chemical structures of phytochemical constituents. The aim of this analysis was to look into the thrombolytic action of Cyperus rotandus methanolic extracts. The fraction's thrombolytic effect was studied in clot lysis experiment. In a thrombolytic activity test, the extract caused 60 % lysis of the blood clot, compared to 70.10 % and 4.70 % lysis for the positive control (streptokinase) and negative control (saline water), respectively. As a result, the extract possessed significant thrombolytic activity. To determine which compounds are responsible for the current pharmacological activities, detailed pharmacological and phytochemical studies are needed. The phytochemical research revealed the presence of phytochemical constituents in various solvent fractions. The presence of these phytochemicals was found to be responsible for the plants' in-vitro thrombolytic action.

Highlights

  • Therapeutic plants are important for the modern composite material, which serves as a new enemy of irresistible experts and can be used to validate pharmacological exercises.Thrombolysis, as well known as thrombolytic healing, is a procedure that dissolves dangerous blood clots, improves blood stream, and prevents tissue and organ damage [1]

  • The aim of our present study was to investigate the thrombolytic activity of methanolic extracts of Cyperus rotandus by using an in vitro procedure

  • The present study indicates high level phytochemical constituents of Tannin, Flavonoids, Polyphenol and Terpenoids from Cyperus rotandus like other plants

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Summary

Introduction

Thrombolysis, as well known as thrombolytic healing, is a procedure that dissolves dangerous blood clots, improves blood stream, and prevents tissue and organ damage [1]. Thrombolysis, known as cluster busting, is the pharmacological degradation (lysis) of blood clumps. The word Cyperus derived from Greek “kuperos” and rotundus from Latin meaning “round.” The family Cyperaceae includes approximately 3000 species of which about 220 species are identified as weeds and of which. Cyperus rotundus L., as well famous as purple nut sedge or nut grass, is a perennial weed with slender, textured crawling rhizomes that are globular on the bottom and emerge individually from tubers that are 1-3 cm tall [3].

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