Abstract

BackgroundThe technique for arterial infusion chemotherapy (HAIC) is not standardized which limits its widely application. The aim of this study was to evaluate the long-term functionality and complications of port-catheter system using percutaneous unilateral trans-femoral implantation with coil only fixed-catheter-tip method.MethodsFrom January 2013 to January 2017, 205 consecutive patients (138 men; aged 28–88 years; mean, 59.1 ± 11.2 years) with unresectable malignant liver tumors underwent percutaneous implantation of side-hole infusion port-catheter into hepatic artery using coil only fixed-catheter-tip method via the unilateral femoral artery. Technical success, procedure time, duration of port functionality, and complications of port dysfunction were investigated.ResultsImplantation technical success was 98.5% and the procedure time was 59.1 ± 10.2 min. Predictable functionality of the port-catheter system at 6-, 12-, and 24 months were 97.5, 89.9, 70.5%, respectively. Complications of port irreversible dysfunction were hepatic artery obstruction (4.0%), catheter occlusion (3.5%), and catheter dislocation (0.5%). Median 5 HAIC cycles (range: 1–14 cycles) were received via port.ConclusionPercutaneous unilateral trans-femoral implantation of a side-hole port-catheter with coils only fixed-catheter-tip method is a simple and feasible interventional technique for HAIC which offers long-term functionality.

Highlights

  • The technique for arterial infusion chemotherapy (HAIC) is not standardized which limits its widely application

  • Techniques of port implantation for Hepatic artery infusion chemotherapy (HAIC) were not made in consensus which limit its widely application

  • Port-catheter system placement is accomplished via surgical laparotomy under general anesthesia

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Summary

Introduction

The technique for arterial infusion chemotherapy (HAIC) is not standardized which limits its widely application. The aim of this study was to evaluate the long-term functionality and complications of port-catheter system using percutaneous unilateral trans-femoral implantation with coil only fixed-catheter-tip method. Techniques of port implantation for HAIC were not made in consensus which limit its widely application. Recent advances in minimally invasive techniques allow percutaneous placement of catheter-port systems under local anesthesia for HAIC [13]. Percutaneous unilateral trans-femoral implantation of a side-hole port-catheter with coils only fixed-catheter-tip method was an and widely performed procedure in our center. The aim of this single center study was to evaluate the experience of 205 consecutive cases of this technique with regard to long-term functionality and complications data

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