Abstract

Objectives: The objective of this study is to examine the benefit of an intra-articular platelet-rich plasma (PRP) injection and to compare this with arthrocentesis in Patients with Temporomandibular Disc Displacement with Reduction. Subjects and Methods: Twenty four patients who did not respond to conservative treatment of anterior disc displacement with reduction were included in this study. They were randomly allocated to one of two study arms: the 'intervention' group who treated with intra articular PRP injection or the control group who treated with Arthrocentesis. Results: In this study, both groups showed significant improvement in TMJ pain, maximum mouth opening (MMO) and clicking 2 weeks after treatment that maintained thereafter. Conclusion: It is possible to conclude that intra-articular PRP injection was equivalent to arthrocentesis regarding reduction of TMJ pain with more beneficial effects of arthrocentesis on MMO and TMJ sound.

Highlights

  • Patients with anterior disc displacement with reduction (DDWR) most frequently suffer from pain which is one of the most common orofacial pains with a prevalence of about 6 % worldwide [1]

  • Objectives: The objective of this study is to examine the benefit of an intra-articular platelet-rich plasma (PRP) injection and to compare this with arthrocentesis in Patients with Temporomandibular Disc Displacement with Reduction

  • They were randomly allocated to one of two study arms: the 'intervention' group who treated with intra articular PRP injection or the control group who treated with Arthrocentesis

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Summary

Introduction

Patients with anterior disc displacement with reduction (DDWR) most frequently suffer from pain which is one of the most common orofacial pains with a prevalence of about 6 % worldwide [1]. Current treatments of the DDWR are largely targeted at symptomatic relief of joint pain and improvement of mandibular range of motion. Treatment approaches vary depending on the symptoms and degree of dysfunction[2]. Treatment regimens can include medication, occlusal appliances, physical therapy modalities, mobilization, exercises, minimally invasive procedures (arthrocentesis and arthroscopic procedures) and open surgical interventions that are only used when all other possible therapeutic options have been exhausted[3,4]. Invasive procedures are recognized increasingly as first line intervention in patients who do not respond to conservative management [5, 6]. Of these procedures, arthrocentesis and intra-articular injectionof platelet rich plasma (PRP) have been applied with varying degrees of success

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