Abstract
Objective: to evaluate the effects of PM and Black Carbon from biomass burning on biomarkers of stress oxidative in schoolchildren residents in the Brazilian Amazon region. Methods: We carried out a cross-sectional study with 200 schoolchildren, aged 6 - 17 years during the dry season of 2012. We assessed the exposure of participants to air pollutants as well as their effects in biomarkers of oxidative stress. We performed regression analysis using generalized linear models to study the association the between oxidative stress biomarkers, and local environmental concentrations of air pollutants for time lags within 0 to 5 days before blood sampling. Results: PM10 and PM2.5 were positively associated with lipid peroxidation biomarker and enzymatic activity of glutathione-s-transferase and inversely associated with components of general thiol (exposure 3-day moving average). Conclusions: Children and adolescents living in the Brazilian Amazon Occidental region showed increase of oxidative stress biomarkers and reducing of thiol group in association with increase of air pollution.
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