Abstract
Cobalt oxide nanoparticles (Co3O4NPs) are used in various devices including magnetic and energy storage, sensors, pigments, and catalysts, thereby imparting enhanced production and use. The current work aims to investigate on the toxicity of Co3O4NPs on fresh water edible snail Pila virens (P. virens). A total of ten P. virens were chosen for acute toxicity studies (96 h) and the lethal concentration (LC50) for Co3O4NPs was found to be 509.45 µg/L. Based on the LC50 value P. virens was exposed to ½ (254 µg/L) and ¼ (127 µg/L) of LC50 concentration for 24 h. The current findings revealed that an increase in lipid peroxidation, catalase, glutathione sulfotransferase, and reduction in reduced glutathione and glutathione peroxidase activity in P. virens upon exposure to 127 and 254 µg/L concentration of Co3O4NPs for 24 h. The Co3O4NPs induced toxicity in fresh water snail P. virens via oxidative stress. P. virens fits as the best organism for the toxicological assessment of Co3O4NPs contaminating the environment.
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